CYP11B1

CYP11B1 gene - Genetics Home Reference - NIH

3 days ago ... The CYP11B1 gene provides instructions for making an enzyme called 11-beta- hydroxylase. This enzyme is found in the adrenal glands, which ...

cyp11b1

CYP11B1

CYP11B1 cytochrome P450 family 11 subfamily B member 1 [ (human)]. Gene ID: 1584, updated on 22-Jan-2020 ...

cyp11b1

CYP11B1 Gene - GeneCards | C11B1 Protein | C11B1 Antibody

CYP11B1 (Cytochrome P450 Family 11 Subfamily B Member 1) is a Protein Coding gene. Diseases associated with CYP11B1 include Adrenal Hyperplasia,  ...

cyp11b1

CYP11B1

The CYP11B1 gene encodes a steroid 11-beta-hydroxylase (EC 1.14.15.4) that functions primarily in mitochondria in the zona fasciculata of the adrenal cortex ...

cyp11b1

Steroid 11β-hydroxylase - Wikipedia

Steroid 11β-hydroxylase is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata. Named officially the cytochrome P450 11B1, mitochondrial, it is a protein that in humans is encoded by the CYP11B1 gene ...

cyp11b1

CYP11B1 - Cytochrome P450 11B1, mitochondrial precursor ...

A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids (PubMed:18215163). Catalyzes the hydroxylation of carbon hydrogen  ...

cyp11b1

Gene: CYP11B1 (ENSG00000160882) - Summary - Homo sapiens ...

Gene: CYP11B1 ENSG00000160882 . twitter logo Twitter facebook logo Facebook email logo Email. Description. cytochrome P450 family 11 subfamily B  ...

cyp11b1

Cyp11b1 MGI Mouse Gene Detail - MGI:88583 - cytochrome P450 ...

View mouse Cyp11b1 Chr15:74834892-74841643 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.

cyp11b1

CYP11B1 gene homepage - Global Variome shared LOVD

3 May 2013 ... General information. Gene symbol, CYP11B1. Gene name, cytochrome P450, family 11, subfamily B, polypeptide 1. Chromosome, 8.

cyp11b1

Tissue expression of CYP11B1 - Summary - The Human Protein Atlas

Summary of CYP11B1 (CPN1, CYP11B, FHI, P450C11) expression in human tissue. Selective granular cytoplasmic expression in adrenal gland.

cyp11b1

CYP11B1 | CYP11, CYP17, CYP19, CYP20 and CYP21 families ...

The IUPHAR/BPS Guide to Pharmacology. CYP11B1 - CYP11, CYP17, CYP19, CYP20 and CYP21 families. Detailed annotation on the structure, function, ...

cyp11b1

CYP11B1 gene symbol report | HUGO Gene Nomenclature Committee

HGNC data for CYP11B1. Approved symbol. CYP11B1. Approved name. cytochrome P450 family 11 subfamily B member 1. Locus type. gene with protein  ...

cyp11b1

Cortisol overproduction results from DNA methylation of CYP11B1 in ...

11 Sep 2019 ... Confirmation of CYP11B1 overexpression in cortisol-producing adenomas. The immunohistochemical analysis of case #1 is shown as ...

cyp11b1

CYP11B1 protein expression summary - The Human Protein Atlas

CYP11B1 (CPN1, CYP11B, FHI, P450C11) protein expression summary.

cyp11b1

CYP11B1 Mutations Causing Non-Classic Adrenal Hyperplasia due ...

CYP11B1, the gene encoding 11β-hydroxylase, is located on chromosome 8q21 –22, tandemly arranged with the CYP11B2 gene encoding aldosterone ...

cyp11b1

Cyp11b1 Null Mouse, a Model of Congenital Adrenal Hyperplasia

6 Feb 2009 ... The Cyp11b1 gene was replaced with a fluorescent reporter gene, and the resultant transgenic line was assessed for reduced 11β-hydroxylase ...

cyp11b1

A mutation in CYP11B1 (Arg-448----His) associated with ... - JCI

1 May 1991 ... Steroid 11 beta-hydroxylase (P450c11) deficiency (failure to convert 11- deoxycortisol to cortisol) causes less than 10% of cases of congenital ...

cyp11b1

CYP11B1 Single Gene | Fulgent Genetics

Sequence variants and/or copy number variants (deletions/duplications) within the CYP11B1 gene will be detected with >99% sensitivity (unless otherwise ...

cyp11b1

Detection and activity of 11 beta hydroxylase (CYP11B1) in the ...

Bovine sequences for CYP11B1, cytochrome P450 aromatase (CYP19A1) and cytochrome P450 17hydroxylase/17,20-lyase (CYP17A1) were obtained from ...

cyp11b1

Gene View - CYP11B1 - cytochrome P450 family 11 ... - RCSB PDB

CYP11B1 - cytochrome P450 family 11 subfamily B member 1 ... UniProt: P15538 , HGNC Approved Gene Symbol: CYP11B1. Previous Symbols: CYP11B ...

cyp11b1

CYP11B1 (cytochrome P450 family 11 subfamily B member 1)

CYP11B1 (cytochrome P450 family 11 subfamily B member 1), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.

cyp11b1

Structure/function relationship of CYP11B1 associated with Dahl's ...

25 Dec 2001 ... Dahl's salt‐resistant normotensive rats (DR rats) have been previously reported to express cytochrome P‐450 (CYP11B1) containing five ...

cyp11b1

A recombinant CYP11B1 dependent Escherichia coli biocatalyst for ...

25 Feb 2019 ... Human mitochondrial CYP11B1 catalyzes a one-step regio- and stereoselective 11β-hydroxylation of 11-deoxycortisol yielding cortisol which ...

cyp11b1

CYP11B1 Antibody (B-11) | SCBT - Santa Cruz Biotechnology

CYP11B1 Antibody (B-11) is a monoclonal CYP11B1 antibody that detects mouse and rat CYP11B1 by WB, IP, IF and ELISA. Cited in 1 publications.

cyp11b1

6M7X: Structure of human CYP11B1 in complex with ... - RCSB PDB

21 Nov 2019 ... Human cytochrome P450 11B1 (CYP11B1) is responsible for the final step generating the steroid hormone cortisol, which controls stress and ...

cyp11b1

Growth Hormone With Aromatase Inhibitor May Improve Height in ...

1 Feb 2019 ... Growth Hormone With Aromatase Inhibitor May Improve Height in CYP11B1 Congenital Adrenal Hyperplasia. Katherine Hawton, Sandra ...

cyp11b1

First Selective CYP11B1 Inhibitors for the Treatment of Cortisol ...

22 Oct 2010 ... Thus, compound 33 (IC50 = 152 nM) is the first CYP11B1 inhibitor showing a rather good selectivity toward the most important steroidogenic ...

cyp11b1

Validation of CYP11B1 and CYP11B2 regulation by microRNA-24 ...

The CYP11B1 and CYP11B2 genes encode the enzymes responsible, respectively, for the terminal stages of cortisol and aldosterone biosynthesis, and have ...

cyp11b1

Missense mutation in CYP11B1 (CGA[Arg-384] → GGA[Gly]) causes ...

Missense mutation in CYP11B1 (CGA[Arg-384] → GGA[Gly]) causes steroid 11β- hydroxylase deficiency. in European Journal of Endocrinology. Authors: Yuichi ...

cyp11b1

Aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1)

Aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) gene expression in the normal and failing rat heart. CA Millar1, P Ye1, GA Gray2, ...

cyp11b1

CYP11B1 - Cytochrome P450 11B1, mitochondrial - Function

NX_P15538 - CYP11B1 - Cytochrome P450 11B1, mitochondrial - Function. Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or ...

cyp11b1

Familial pericentric inversion chromosome 3 and R448C mutation of ...

27 Mar 2014 ... Familial pericentric inversion chromosome 3 and R448C mutation of CYP11B1 gene in Turkish kindred with 11β-hydroxylase deficiency.

cyp11b1

Cyp11b1 (cytochrome P450, family 11, subfamily b, polypeptide 1 ...

25 May 2000 ... ENCODES a protein that exhibits steroid 11-beta-monooxygenase activity; steroid binding; INVOLVED IN adenosine metabolic process; ...

cyp11b1

KEGG ORTHOLOGY: K00497

KEGG Orthology (KO) [BR:ko00001] 09100 Metabolism 09103 Lipid metabolism 00140 Steroid hormone biosynthesis. K00497 CYP11B1; steroid 11beta- ...

cyp11b1

CYP11B1 Gene Mutations in Patients with Congenital Adrenal ...

CYP11B1 Gene Mutations in Patients with Congenital Adrenal Hyperplasia in Turkey. Firdevs Basa, Berrin Ergun-Longmireb, Nurcin Sakaa, Guven Toksoyc, ...

cyp11b1

The Interaction of Bovine Adrenodoxin with CYP11A1 (Cytochrome ...

28 Sep 2001 ... Rate constants for the formation of the reduced CYP11A1·CO and CYP11B1·CO complexes by wild type adrenodoxin, the adrenodoxin mutants ...

cyp11b1

CYP11B1 [mitochondrial inner membrane] - Reactome

CYP11B1 [mitochondrial inner membrane]. Stable Identifier. R-HSA-193978. Type. Protein [EntityWithAccessionedSequence]. Species. Homo sapiens.

cyp11b1

CYP11B1 ELISA Kit (Rat) (OKCD01256) | Quantitative Sandwich ...

CYP11B1 ELISA Kit (Rat) (OKCD01256) | Quantitative Sandwich ELISA | Sample Types: Tissue homogenates, cell lysates and other biological fluids. | Species ...

cyp11b1

Anti-CYP11B1/Cytochrome P450 11B1, mitochondrial Antibody

Polyclonal antibody for CYP11B1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. CYP11B1 information: Molecular ...

cyp11b1

Biotransformation of the mineralocorticoid receptor antagonists ...

Human CYP11B1 and CYP11B2 are shown to convert spironolactone and canrenone. •. Metabolites are identified by NMR as 11β-, 18- and 19- hydroxylated ...

cyp11b1

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